Reducing background in MHC tetramer assays: Characterization of a new commercially available MHC tetramer for the violet laser - Brilliant!

MHC tetramer reagents, comprised of biotinylated MHC peptide monomers complexed with a fluorochrome-labeled streptavidin, have been used for detection of antigen-specific T cells by flow cytometry for nearly two decades. 

 

MHC_TetramerAssays_Scientific