Metal-Conjugated NeutrAvidin for MHC Multimer Assays Using Mass Cytometry

Antigen-specific T cells in blood can be detected through the use of soluble MHC-peptide ligands that engage αβTCR. T cell receptors (TCRs) expressed on T cells specifically recognize and bind to complexes of major histocompatibility complex (MHC) molecules and peptide fragments.

 

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