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p62/Sqstm1: The molecule that links autophagy to the Keap1-Nrf2 system

This white paper, authored by Dr. Masaaki Komatsu and Dr. Yoshinobu Ichimura of Niigata University, details how Autophagy and the Keap1-Nrf2 system are cell defense mechanisms induced in response to environmental stress. Cells are protected by autophagy via the degradation of cytotoxic cellular components in the lysosome and by the Keap1-Nrf2 system via the induction of expression of antioxidant proteins.  Learn more by downloading this white paper today!